Here, Creative Biolabs has established a time-saving and labor-saving Hybridoma platform to quickly and effectively provide global clients convenient and high-quality hapten-specific hybridoma screening services. https://small-molecule-antibody.creative-biolabs.com/screening-for-positive-hybridoma-cells-by-flow-cytometry.htm

The hybridoma method is a mainstay for monoclonal antibody (mA😎 production (including the hapten-associated small molecule antibody), during the whole workflow, the accurate and specific screening of positive hybridomas usually determines the success. Commonly, positive antibody-secreting subclones are screened and selected by a solid-phase enzyme-linked immunosorbent assay (ELISA). https://small-molecule-antibody.creative-biolabs.com/screening-for-positive-hybridoma-cells-by-elisa.htm

Haptens are non-immunogenic small molecules and usually need conjugating to carrier proteins, such as BSA (bovine serum albumin) and KLH (keyhole limpet hemocyanin) in order to expose the small molecule epitope in some ways. https://small-molecule-antibody.creative-biolabs.com/custom-services-for-anti-hapten-antibody.htm

The successful production of desired antigen-special antibodies depends on multiple factors, including but not limited to the design and modification of hapten, selection of the appropriate carrier protein and the method of conjugation. https://small-molecule-antibody.creative-biolabs.com/custom-services-for-anti-hapten-antibody.htm

Creative Biolabs offers Cancer Cell Line Screening Service, which is based on a well-validated, large-scale cell panel screening platform, to enable speedy, cost-effective, and large-scale cancer cell line screening. Early in the drug development process, we can help clients obtain critical information on the cytotoxicity and chemotherapeutic potential of medicines. https://discovermp.creative-biolabs.com/cancer-cell-line-screening-service.htm

The introduction of shRNA into mammalian cells through infection with viral vectors allows for stable integration of shRNA and long-term knockdown of the targeted gene. Creative Biolabs offers different approaches to knock down the membrane protein of interest. https://discovermp.creative-biolabs.com/membrane-protein-knockdown-cell-line-development.htm

Creative Biolabs offers membrane protein stable cell line that can overexpress, knockdown, or knockout the target protein of interest to help our clients for membrane protein expression, membrane protein antibody discovery, membrane protein functional studies, membrane protein drug screening etc. https://discovermp.creative-biolabs.com/membrane-protein-stable-cell-line-development-services.htm

Cell disruption yields a membrane fragments/vesicles suspension containing the membrane proteins and other material as contaminants. Depending on the purification technique employed, these contaminants will be removed. https://discovermp.creative-biolabs.com/